Lowdown on Roundup Part I

Bayer, 2002

Bayer, 2002, Glyphosate Herbicide Label, EPA Registration Number: 72155-16.


Early Bayer glyphosate herbicide label. FULL TEXT

Benbrook, 2016a

Charles M. Benbrook, “Trends in glyphosate herbicide use in the United States and globally,”  Environmental Sciences Europe, 2016, 28:3, DOI 10.1186/s12302-016-0070-0.


BACKGROUND: Accurate pesticide use data are essential when studying the environmental and public health impacts of pesticide use. Since the mid-1990s, significant changes have occurred in when and how glyphosate herbicides are applied, and there has been a dramatic increase in the total volume applied.

METHODS: Data on glyphosate applications were collected from multiple sources and integrated into a dataset spanning agricultural, non-agricultural, and total glyphosate use from 1974–2014 in the United States, and from 1994–2014 globally.

RESULTS: Since 1974 in the U.S., over 1.6 billion kilograms of glyphosate active ingredient have been applied, or 19 % of estimated global use of glyphosate (8.6 billion kilograms). Globally, glyphosate use has risen almost 15-fold since so-called “Roundup Ready,” genetically engineered glyphosate-tolerant crops were introduced in 1996. Two-thirds of the total volume of glyphosate applied in the U.S. from 1974 to 2014 has been sprayed in just the last 10 years. The corresponding share globally is 72 %. In 2014, farmers sprayed enough glyphosate to apply ~1.0 kg/ha (0.8 pound/ acre) on every hectare of U.S.-cultivated cropland and nearly 0.53 kg/ha (0.47 pounds/acre) on all cropland worldwide.

CONCLUSIONS: Genetically engineered herbicide-tolerant crops now account for about 56 % of global glyphosate use. In the U.S., no pesticide has come remotely close to such intensive and widespread use. This is likely the case globally, but published global pesticide use data are sparse. Glyphosate will likely remain the most widely applied pesticide worldwide for years to come, and interest will grow in quantifying ecological and human health impacts. Accurate, accessible time-series data on glyphosate use will accelerate research progress.  FULL TEXT

Dow, 1999

Dow Agro Sciences, 1999, Glyphosate Herbicide Label, EPA Registration Number: 62719-319.


Label for one of Dow’s first glyphosate-based herbicides.  FULL TEXT

EPA, 1993

Environmental Protection Agency, “Reregistration Eligibility Decision (RED): Glyphosate,” Office of Prevention, Pesticides, and Toxic Substances, September 1993.


All pesticides sold or distributed in the United States must be registered by EPA, based on scientific studies showing that they can be used without posing unreasonable risks to people or the environment. Because of advances in scientific knowledge, the law requires that pesticides which were first registered years ago be reregistered to ensure that they meet today’s more stringent standards. In evaluating pesticides for reregistration, EPA obtains and reviews a complete set of studies from pesticide producers, describing the human health and environmental effects of each pesticide. The Agency imposes any regulatory controls that are needed to effectively manage each pesticide’s risks. EPA then reregisters pesticides that can be used without posing unreasonable risks to human health or the environment. When a pesticide is eligible for reregistration, EPA announces this and explains why in a Reregistration Eligibility Decision (RED) document. This fact sheet summarizes the information in the RED document for glyphosate.  FULL TEXT

Franz, 1974

Franz, John E., “N. Phosphonomethyl-glycine Phytotoxicant Compositions,” U.S. Patent 3,799,758, March 26, 1974.


N-phosphonomethylglycine and novel derivatives thereof useful as phytotoxicants or herbicides.


Franz, 1983

Franz, John E., September 20, 1983, “Salts of N-Phosphonomethyl glycine,” U.S. Patent # 4,405,531.


N-phosphonomethylglycine and novel derivatives thereof useful as phytotoxicants or herbicides.  FULL TEXT


Micro Flo, 1999

Micro Flo (BASF subsidiary), 1999, Glyphosate Herbicide Label, EPA Registration Number: 51036-312.


First BASF company glyphosate herbicide label. FULL TEXT

Monsanto, 1994

Monsanto, 1994, Roundup Ultra Herbicide Label.


First herbicide label for Roundup Ultra. Full Text

Monsanto, 1996

Monsanto, 1996, Roundup Herbicide Label, EPA Registration Number: 524-445.


First label for Roundup Ready soybeans.  FULL TEXT

Monsanto, 2002

Monsanto, 2002, Ultra Max II Herbicide Label, EPA Registration Number 524-537.


First Ultra Max II glyphosate herbicide for Roundup Ready crops label.  FULL TEXT